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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANAPC1
All Species:
13.03
Human Site:
S518
Identified Species:
26.06
UniProt:
Q9H1A4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1A4
NP_073153.1
1944
216500
S518
I
P
G
L
P
A
P
S
L
T
M
S
N
T
M
Chimpanzee
Pan troglodytes
XP_515601
1394
155989
I34
F
Q
Q
L
G
T
Y
I
H
S
I
R
D
P
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532958
1943
216470
S517
I
P
G
L
P
A
P
S
L
T
M
S
N
T
M
Cat
Felis silvestris
Mouse
Mus musculus
P53995
1944
216068
S518
I
P
G
L
P
A
P
S
L
T
M
S
N
M
M
Rat
Rattus norvegicus
NP_001101241
1944
216060
S518
I
P
G
L
P
A
P
S
L
T
M
S
N
M
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419303
1945
216100
L520
P
G
L
P
A
P
S
L
T
M
S
N
Q
M
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921168
1979
220132
F518
P
G
L
L
S
P
T
F
S
V
P
N
Q
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573025
2030
227256
V569
A
S
P
A
P
S
H
V
K
T
P
M
A
A
A
Honey Bee
Apis mellifera
XP_001122449
1939
218025
V510
I
M
D
L
S
N
G
V
V
L
Y
S
G
V
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202400
910
100394
Poplar Tree
Populus trichocarpa
XP_002312165
1929
212815
D503
S
D
Y
L
S
R
A
D
S
S
V
D
S
E
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196175
1678
186257
I318
V
P
V
I
C
F
L
I
L
E
Q
K
K
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
N.A.
97.3
N.A.
92.1
92.9
N.A.
N.A.
81.7
N.A.
66
N.A.
33.6
38
N.A.
25.2
Protein Similarity:
100
71.5
N.A.
98.5
N.A.
96
96.5
N.A.
N.A.
90.2
N.A.
79
N.A.
52.2
59.1
N.A.
33.8
P-Site Identity:
100
6.6
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
6.6
N.A.
13.3
20
N.A.
0
P-Site Similarity:
100
33.3
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
20
26.6
N.A.
0
Percent
Protein Identity:
28.5
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
47
N.A.
N.A.
45.8
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
9
34
9
0
0
0
0
0
9
9
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
0
9
0
0
0
9
9
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% E
% Phe:
9
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
17
34
0
9
0
9
0
0
0
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% H
% Ile:
42
0
0
9
0
0
0
17
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
0
9
9
0
0
% K
% Leu:
0
0
17
67
0
0
9
9
42
9
0
0
0
9
9
% L
% Met:
0
9
0
0
0
0
0
0
0
9
34
9
0
25
34
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
17
34
0
0
% N
% Pro:
17
42
9
9
42
17
34
0
0
0
17
0
0
17
17
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
9
0
17
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% R
% Ser:
9
9
0
0
25
9
9
34
17
17
9
42
9
0
0
% S
% Thr:
0
0
0
0
0
9
9
0
9
42
0
0
0
17
9
% T
% Val:
9
0
9
0
0
0
0
17
9
9
9
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
9
0
0
0
9
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _